Skin cancer is increased by some medicines used to treat MPNs. I have a kidney transplant, and I have to take immunosupressive drugs that greatly increase my chances of skin cancer. I stay out of the sun, and see a dermatologist twice a year.

Skin cancers have an increased risk with MPNs. But in the material I’ve read, it sounds like many of the secondary cancers depend on the mutations identified, and those are determined by the bone marrow biopsy report. It seems like more mutations have been discovered even in the four years since I was diagnosed with PV and ET. Someone here will pop up with more information for you. There are so many variables in each of our cases, so be careful to not get depressed when you read the stories of many in what sound like dire situations. You will hopefully believe in your care team that they are trying to do the best for you. It is preferable to all of us to be under the care of an MPN expert. However, sometimes logistics and distance from one of their centers makes it impossible to have the best opinion at the time we feel we need it. Of course, you are scared when in an increased stage of MF, and it is good that you are asking the question which will hopefully give you some direction and good advice. Blessings to you, Heather!!

Here is a comprehensive abstract in a PubMed issue in 2021 that you may find helpful in researching skin cancers especially in MPNs treated with hydroxyurea.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC84...