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Real members of myMPNteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Does anyone here know if JAK2 inhibitor meds work if you are JAK2 negative? Just curious...I'll ask my doc next visit as well.

A myMPNteam Member asked a question 💭
Galway, IE
August 6, 2023
 · 
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A myMPNteam Member

Hi IrishHiker!

This study below gives a nice explanation regarding JAK inhibitors in myeloproliferative neoplasms 👇
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC36...
You do not need to have a JAK-positive MPN for JAK inhibitors to be useful.

Best regards,
Tatiana

August 6, 2023
A myMPNteam Member

I have MF with negative Jak2. I take Jakafi. Goal is to decrease my spleen size. I will not know if working till after six months. I'm about to enter my 5th month this month (Aug)

August 7, 2023
A myMPNteam Member

Thank you

August 6, 2023

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