If I were in your position, I would find a neonatologist to consult. I'd want to know if there are in utero therapies maybe to place stem cells that aren't predisposed to jak2 or mpn. Stem cells in fetuses may not be differentiated yet and might be susceptible to added stem cells influence. Or what diagnostic genetic testing can be done before or at birth? Then you might want a biologic offspring and monitor the child for abnormal cbc and genetic tests. Diagnosing early and treating early may make for a normal lifespan especially since in 5, 10, or 20 years there will be newer medications. But, start with an experienced and smart MPN specialist at a major medical center to ask.

It can be genetic, I have ET, my dad has PV and my uncle had ET. But the chance to pass it to the child is 50%. My sister and cousins don’t have any MPNs yet (it can develop after 40y old or after 60y old).

i was told that Jak2 develops and a person is not born with it.

They say that MPns are not genetic but my wife has had PV and now on to MF for over 11 years and her mom passed several years ago from Leukemia. We have no idea if she was suffering from PV or MF before getting LK, but I think in my mind that it’s possible to pass down.

Same here. I have been recently diagnosed and my wife is pregnant. I'm concerned if it inherited to our child ...