That seems like an odd thing to prescribe for someone with ET. Naltrexone is customarily used to treat someone who has been addicted to opioids, or to those with things like fibromyalgia or chronic pain syndrome. It is anti-inflammatory treatment for the latter.

I did use it (LDN) for a while but did not notice any positive effects on my platelet production or overall wellbeing
I continue with aspirin, vitamin supplements & maintain a reasonably healthy lifestyle.

I don’t know how old this thread is but there is interesting developments in the off-label use of LDN, specifically in the treatment of fibromyalgia and chronic fatigue syndrome. Also, it is being used in post-viral conditions such as long COVID to alleviate inflammation and a strange internal tremor (from which I suffer). All things being equal, I am looking at starting LDN to treat the tremors and am hopeful that it will also have a beneficial effect on fatigue and inflammations that come along with my PMF.

I would be interested to hear if your started it @A myMPNteam Member and how it goes for you.
https://www.verywellhealth.com/low-dose-naltrex...
https://www.verywellhealth.com/low-dose-naltrex...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10...

Mentioned Users

A myMPNte...

LDN for Fibromyalgia & Chronic Fatigue Syndrome

https://www.verywellhealth.com/low-dose-naltrexone-ldn-for-fibromyalgia-cfs-716070

Low-Dose Naltrexone Could Treat Long COVID Symptoms

https://www.verywellhealth.com/low-dose-naltrexone-long-covid-treatment-7507283

LDN isn't the same as Naltrexone. It's all in the dosage!. LDN has been very successful in the treatment of CFS/ME etc.

Interesting…I’ve heard of it being used with Chronic Pain.